With the return of Marvel's Agents of S.H.I.E.L.D. this March, the series has already added a new villain to face our heroes with Emmy-winning actress Drea de Matteo! Matteo will play Karla Faye Gideon, a Gifted woman with a grudge to bear against S.H.I.E.L.D. who joins forces with Skye's father, Cal. Here's what Jeph Loeb, Executive Producer and Marvel's Head of Marvel Television, had to say about the casting in a statement.

"We're thrilled to have Drea join us as yet another great villain to challenge our cast. We relished the opportunity to work with her in such a menacing role."

Matteo earned an Emmy for her role as Adriana La Cerva in The Sopranos, and since then has starred in series such as Sons of Anarchy, Desperate Housewives and Joey. Marvel's Agents of S.H.I.E.L.D. is Executive Produced by Joss Whedon (Marvel's The Avengers, Buffy the Vampire Slayer); Jed Whedon & Maurissa Tancharoen, (Marvel's Agents of S.H.I.E.L.D. pilot co-writers, Dollhouse, v); Jeffrey Bell (Angel, Alias); and Jeph Loeb (Marvel's Agent Carter, Marvel's Daredevil, Lost).

Marvel's Agents of S.H.I.E.L.D. is produced by Marvel Television and ABC Studios. Marvel's Agents of S.H.I.E.L.D. returns on Tuesday, March 3 at 9:00 p.m. ET on ABC. For more information on the series and the other exciting Marvel Television projects, stay tuned to Marvel.com.