According to Variety, Billy Crudup, Mandy Moore, Harvey Keitel, Mia Farrow and Bob Balaban will star in Plum Pictures' romantic comedy "Dedication," on which thesp Justin Theroux will make his directorial debut.

Lensing is scheduled for early next year in Manhattan. Theroux developed the script with scribe David Bromberg.

The plot concerns a misogynistic children's book writer (Crudup) who is forced to collaborate with a young female illustrator (Moore) when his writing partner and only friend (Keitel) dies. Farrow will play the domineering mother of Moore's character, Balaban the book's publisher.

Plum principals Celine Rattray, Galt Niederhoffer and Daniela Taplin will produce.