Jonathan Levine directs 50/50 from a script by Will Reiser, based on the author's own real-life bout with cancer. In the film, Anjelica Huston plays a wife whose husband has been diagnosed with Alzheimer's. As she comes to terms with that, she then discovers that her son (Joseph Gordon-Levitt) has cancer. Our own Paulington James Christensen III recently caught up with the iconic actress to talk about her role in this hilarious and heartwarming film. Check out our exclusive interview below.