After two straight weekend wins in theaters, Marvel's Doctor Strange is a hit, taking in nearly $500 million at the worldwide box office after just fourteen days in theaters. This weekend the Marvel Phase 3 adventure faces its biggest test yet, going up against Warner Bros.' highly-anticipated Harry Potter spin-off Fantastic Beasts and Where to Find Them, along with Open Road Films' true story adaptation Bleed For This and STX Entertainment's teen comedy The Edge of Seventeen. It should be no contest for Fantastic Beasts and Where to Find Them, which could have a runaway victory with a whopping $72.5 million.

While $72.5 million is certainly a great opening by many standards, it would actually mark the "worst" opening in the Harry Potter franchise. As of now, the lowest opening weekend in the Harry Potter franchise is the $77.1 million earned by Harry Potter and the Order of the Phoenix in 2007. Still, that tally should be more than enough to take down Doctor Strange, which we're projecting will drop into second place this weekend with $24.6 million.

Box Office Mojo is projecting that Fantastic Beasts will open in more than 4,000 theaters across the country, which may or may not be the widest release in theaters this weekend. DreamWorks Animation's Trolls screened in 4,066 theaters last weekend, but we don't know if the studio will alter its theater count for the animated hit's third frame in theaters. The boxing drama Bleed For This is expected to debut in roughly 2,000 theaters, while The Edge Of Seventeen is projected to debut in 1,800 theaters. Billy Lynn's Long Halftime Walk is also expanding into 1,100 theaters nationwide this weekend.

All three of this weekend's newcomers are critical hits, with Fantastic Beasts and Where to Find Them currently possessing an impressive 97% rating on Rotten Tomatoes, with The Edge of Seventeen sitting at 89% and Bleed For This pulling in a 74% rating. Those numbers could very well change as we get closer to opening day, but all three are winning over critics. Rounding out the top 5 after Fantastic Beasts and Where to Find Them and Doctor Strange will be Trolls in third place with $19.6 million, followed by Arrival with $14.2 million.

Fantastic Beasts and Where to Find Them opens in 1926 as Newt Scamander has just completed a global excursion to find and document an extraordinary array of magical creatures. Arriving in New York for a brief stopover, he might have come and gone without incident...were it not for a No-Maj (American for Muggle) named Jacob, a misplaced magical case, and the escape of some of Newt's fantastic beasts, which could spell trouble for both the wizarding and No-Maj worlds.

Bleed For This is the incredible true story of one of the most inspiring and unlikely comebacks in sports history. Miles Teller (Whiplash, Divergent) stars as Vinny "The Pazmanian Devil" Pazienza, a local Providence boxer who shot to stardom after winning two world title fights. After a near-fatal car accident leaves Vinny with a severed spine, he is told he may never walk again. Against all odds and doctor's orders, renowned trainer Kevin Rooney (Aaron Eckhart) agrees to help Vinny return to the ring just a year after the accident for what could be the last fight of his life.

Everyone knows that growing up is hard, and life is no easier for high school junior Nadine (Hailee Steinfeld), who is already at peak awkwardness when her all-star older brother Darian (Blake Jenner) starts dating her best friend Krista (Haley Lu Richardson) in The Edge of Seventeen. All at once, Nadine feels more alone than ever, until the unexpected friendship of a thoughtful boy (Hayden Szeto) gives her a glimmer of hope that things just might not be so terrible after all. The supporting cast includes Woody Harrelson, Kyra Sedgwick, Nesta Cooper and Christian Michael Cooper.

The top 10 will be rounded out by Almost Christmas ($8.2 million), Hacksaw Ridge ($6.1 million) Billy Lynn's Long Halftime Walk ($5.6 million), The Edge of Seventeen ($4.1 million) and The Accountant ($2.2 million). Also opening in limited release is Magnolia's horror-thriller The Eyes of My Mother, Well Go USA's dramatic comedy I Am Not Madame Bovary, Roadside Attractions' drama Manchester by the Sea, Focus Features' thriller Nocturnal Animals, Magnolia's action movie Officer Downe, Cleopatra Films' dramatic comedy A Street Cat Named Bob and High Top Releasing's action movie The Take. We don't know if these films will be expanding nationwide in the weeks to come.

Looking ahead to next weekend, four new films arrive in wide release, ahead of the Thanksgiving holiday. Opening on Wednesday, November 23 is Disney's Moana, Paramount's Allied, Broad Green Pictures' Bad Santa 2 and 20th Century Fox's Rules Don't Apply. On Friday, November 25, a number of films arrive in limited release, such as Oscilloscope Pictures' Always Shine, IFC's Evolution, Independent's Kill Command, The Weinstein Company's Lion, EuropaCorp's Miss Sloane and Strand's documentary Mifune: The Last Samurai. Take a look at the projected top 10 for the weekend of November 18, and check back on Sunday for the box office estimates.