While no offers have gone out yet, Hugh Jackman is reportedly the front runner for a lead role, although specifics on his character were not revealed. The story centers around a team of scientists who shrink themselves into a a tiny ship. They are injected into the bloodstream of a sick colleague and must find out what is wrong with him to save his life.
We reported back in February that Shawn Levy will direct Fantastic Voyage, a 3D adventure which will also be produced by James Cameron. Laeta Kalogridis (Avatar, Shutter Island) wrote the screenplay for the remake along with Shane Salerno. The original Fantastic Voyage was released in 1966 and starred Stephen Boyd, Raquel Welch, and Donald Pleasence.
It isn't clear when production will start on Fantastic Voyage, since it has not been given the green light as of yet. It is said that, once the scientists are inside the body, the 3D movie will be completely CGI.