Bridesmaids debuts in second place with a solid $24.5 million while Priest opened in fourth place with $14.5 million.
Fast Five drops to second place with $32.5 million while Jumping the Broom debuts in third place with $13.7 million.
Tyler Perry's latest effort is predicted to pull in $30 million, but will it fend off Rio.
The writer/director/producer/actor has extended his first look partnership with his longtime studio for two more years.
The "Old Spice guy" will star alongside Loretta Devine and Bow Wow.
The studio has set an April 22, 2011 release date for Tyler Perry's 11th film.