Oded Fehr is reprising his role as Carlos Olivera in the upcoming third installment of the Resident Evil series. Paul W.S. Anderson, who wrote the first two films, is returning to write Resident Evil: Extinction, which will be directed by Russell Mulcahy. Also joining the cast is Mike Epps and Iain Glen as Dr. Isaacs.

Milla Jovavich is back as Alice to run with a new pack of humans, leading a caravan that's cutting through the Nevada desert on a long trek to Alaska. Hunted by the minions of the perpetually scheming Dr. Isaacs, Alice has zombies hungry for her flesh and lab rats hungry for her blood. All Alice wants is revenge.

Production is scheduled to begin mid-May in Mexicali, Mexico.