According to Variety, Paul Giamatti has signed with Sci Fi Channel to voice the lead character in the animated series pilot Amazing Screw-On Head, from exec producers Bryan Fuller ("Wonderfalls") and Jason Netter.

The cabler last year quietly commissioned the pilot, based on Mike Mignola's (Hellboy) comicbook of the same name.

David Hyde Pierce, Molly Shannon and Patton Oswalt also will lend their voices to the project.

Giamatti will voice Screw-On Head, a Civil War-era secret agent at the service of president Abraham Lincoln and an unsung hero who never made it into the history books. His special power is the ability to screw his head onto a variety of different bodies. Hyde Pierce plays Emperor Zombie, Shannon voices Patience the Vampire and Oswalt is Mr. Groin.

Screw-On Head has a "bit of James Bond" but with a "completely absurdist twist," Mark Stern, Sci Fi exec VP of programming, said. "It's like the 1860s kind of wild, wild West ... on acid." Cabler execs hope to see a finished pilot by early next year.