Director Paul W.S. Anderson revealed in a recent profile that Resident Evil 6 will begin production this fall. The director is currently shooting Pompeii in Toronto, which means he will likely move directly from that project into Resident Evil 6.
A specific start date was not released, but we reported in March that Sony Pictures has issued a September 13, 2014 release date. Franchise star Milla Jovovich will return as Alice, although no other cast members have been confirmed. The last installment, Resident Evil: Retribution, featured the return of several cast members from previous Resident Evil movies, such as Sienna Guillory, Michelle Rodriguez, and Boris Kodjoe.