In Season 3's finale, Jesse (Aaron Paul) was on the run, with Mike (Jonathan Banks) in hot pursuit, while Walt (Bryan Cranston) negotiated for his life with Gus (Giancarlo Esposito). In a desperate attempt to escape certain death, Walt concocted a disturbing plan - kill his former lab assistant Gale - to provide for his and Jesse's safety. The scheme ultimately forced Jesse to Gale's doorstep with a gun while Walt was held hostage in the Superlab.
Walt and Jesse face the deadly consequences of their actions. Skyler deals with a puzzling disappearance, as Marie struggles to help Hank with his recovery.
Walt attempts to form a new alliance as he plans his next move. Skyler pushes Walt towards a business opportunity, in hopes of protecting the family.
Events spiral out of control at Jesse’s place. Skyler reluctantly asks for Saul’s help. Marie returns to an old pastime and a friend asks Hank for help.
The Cartel takes steps to gain the upper hand. Walt and Skyler share an embarrassing secret with the rest of the family. Jesse’s activities draw unwanted attention.
When Jesse goes missing, Walt fears the worst. Skyler has an unlikely reunion. Hank shares some bad news with Detective Tim Roberts.
Skyler makes an unsettling discovery. Walter, Jr. pushes his dad into a questionable purchase. Jesse offers Mike some unexpected help.
A frustrated Walt gambles on a risky new plan. Skyler's business venture hits a snag. Hank recruits Walter, Jr. for an unusual outing.
Skyler develops an unusual solution to her money troubles. Hank enlists Walt to investigate a theory. Walt’s impatience with Jesse grows.
Skyler's past mistakes come back to haunt her. Gus takes action to thwart his rivals. Jesse seeks Walt's help, with mixed results.
Walt's family worries when he doesn't turn up for Walter, Jr.'s 16th birthday. Jesse is forced to put his lab skills to the test without Mr. White's help.
Walt takes drastic action to protect his secret and Gus. Skyler's efforts to solve Ted's financial problems hit a wall.
Hank pushes Gomez to pursue one last lead, while Walt struggles to protect the family. Jesse gets alarming news and rushes to meet with Mr. White.
As Jesse faces police scrutiny for his comments to Andrea, Walt desperately plots to gain the upper-hand within his season-long game of wits with meth kingpin Gus.