A patient who underwent routine liposuction surgery is found dead in the recovery room; surgeons operate on a priest whose sex organ was bitten off; Geiger refuses to operate on a dying boy.
Geiger and Watters clash over which dying patient should receive a donor heart: a wealthy philanthropist about to give millions to the hospital or a humble newsstand vendor.
A surgeon afflicted with Tourette syndrome prepares to operate on a newborn; Hanlon’s patient hopes plastic surgery will transform her into a Barbie lookalike; a man donates Albert Einstein’s brain to the hospital.
A risk management committee investigates McNeil’s amputation of a young baseball player’s arm; Shutt deals with a young unidentified girl who is unable to speak.
Cacaci attempts suicide by jumping off the hospital’s rooftop, prompting doctors and ex-wives to reflect upon their feelings about the enigmatic doctor.
Alberghetti and an obstetrician attempt to impregnate a patient after the woman miscarries and her husband dies of a heart attack; the hospital finds itself in the midst of a rodent crisis.
An outbreak of a deadly disease forces the hospital to be quarantined.
As Thanksgiving approaches…Geiger and Alberghetti fight to save a patient’s life by watching a satellite feed of a surgeon in Sri Lanka performing an experimental procedure.
An armed man traps McNeil and Shutt in a warehouse with critically injured gunshot victims; Hanlon and Alberghetti fight to save the life of a stabbing victim.
Hanlon attempts to convince a Laotian refugee to undergo cancer surgery; a man with a heart condition believes his body jewelry protects him from harm.
A woman believes her comatose husband is a conduit for the Lord; in his quest to fund a new coronary unit, Geiger discovers a doctor experimenting with human cloning in the hospital’s basement.
Wilkes’ estranged aunt attempts to save a man infected with tuberculosis; Simon is stymied by a patient whose ailment cannot be identified.
The surgeons assist a castrated teenager whose parents raised him as a girl; Simon uses an experimental treatment on an Alzheimer’s sufferer.
A man must choose which of his two children is to receive a liver transplant; police charge McNeil with involuntary manslaughter after one of his patients dies after taking Viagra; Simon suspects Rose Weber is addicted to her seizures.
Geiger juggles two crises simultaneously when his daughter is diagnosed with a life-threatening heart ailment and hospital board members demand drastic budget cuts; Hanlon performs an appendectomy on co-joined twins.
Simon comes to the aid of a mentally challenged couple who wish to start a family.
Shutt and Simon fight to save the life of an eleven-year-old girl with a seemingly inoperable brain aneurysm; steroid use catches up to a female pro-wrestler; Wilkes and his son come to the aid of an ailing tarantula.
Doctors fight to the save the lives of co-joined twins when one is diagnosed with cancer; McNeil’s childhood mentor seeks help for a gunshot wound and asks McNeil to keep quiet about how it happened.
Charismatic Hugh Miller takes over the hospital when it is sold to an HMO; Simon and Shutt attempt to save the life of a fetus with an enlarged head by performing surgery in the mother’s womb.
Simon and Shutt wire a paralyzed patient’s brain to a computer; McNeil encounters a mountain of HMO bureaucracy when one of his patients requires hip replacement surgery.
While recovering from a heart attack, Miller befriends a dying patient whose survival depends on cutting through HMO red tape; a woman regains consciousness after being in a coma for fifteen years.
When the hospital is put up for sale, Miller purchases stock in a company owned by a paralyzed computer genius who is about to undergo an experimental operation that utilizes his company’s technology, leaving hospital’s ultimate fate in McNeil’s hands.