The fifth season of Monk originally aired in the United States on USA Network from July 7, 2006 to March 2, 2007. It consisted of 16 episodes. Tony Shalhoub, Traylor Howard, Ted Levine, and Jason Gray-Stanford reprised their roles as the main characters. A DVD of the season was released on June 26, 2007.
A famous actor preparing to play Monk gets a little too close to one of Monk's real-life murder investigations.
When a union boss' death threatens to prolong a city-wide garbage strike in San Francisco, it's up to Monk to help end the strike by determining whether the boss' death was suicide or murder.
Julie and her friends hire Monk to look into the suspicious death of their basketball coach.
Monk tries to solve a murder after losing his eyesight.
When Natalie convinces Monk to go into business as a private eye, his first case is a seemingly innocuous fender bender that leads to a far more dangerous investigation.
Monk attends his college reunion and uncovers a complex murder plot against one of his former classmates.
When Dr. Kroger retires after his cleaning lady is killed, it's up to Monk to solve the case and get Dr. Kroger back to work.
Monk goes to a rock concert to look for Captain Stottlemeyer's son and finds himself in the middle of a murder investigation.
When Monk's truck driving father rolls into town at Christmastime, Monk joins him on the road, where they stumble across a very peculiar mystery.
A missing millionaire suffering from leprosy comes out of hiding to hire Monk, who soon finds himself in the midst of a shadowy murder plot worthy of a classic Hollywood film noir.
A fun-loving everyman named Hal bumps into Monk, and the two become fast friends. For the first time in his life, Monk appears to have a buddy. But is Hal up to something?
When Natalie suspects foul play in the deaths of her parents' wealthy neighbors, Monk goes undercover as a butler to investigate.
Monk goes toe to toe with a popular radio shock jock who is suspected of killing his wife.
When Lt. Disher inherits a farm from an uncle who committed suicide, he decides to quit the police force and start a new life in the country. But Disher soon suspects that his uncle was murdered, so Monk joins him on the farm to investigate.
When the mysterious “Six Way Killer” strikes in San Francisco, Monk matches his detective skills against the flashy forensic technology of a federal agent as they both pursue the murderer.
Monk goes to the emergency room for a bloody nose, but when a doctor in the hospital turns up dead, Monk joins the murder investigation, and soon his own life is in grave danger.