Nami's log pose begins to point to the sky, after that, a big ship falls from sky and the crew finds a map in of an island named 'Skypiea' on a 200-year-old ship. They compete with the monkey-like Masira's salvage crew while they search for more clues on how to get there.
The Straw Hats decide to go to Jaya island to look for information on Skypeia. Meanwhile, Ace suddenly shows up on Buggy's ship; Buggy doesn't let any of his men attack Ace, fearing Whitebeard's retribution.
Jaya's main town is full of famous pirates that are constantly brawling with each other. Luffy and Zoro have a run-in with a pirate known as 'Bellamy the Hyena,' who ridicules their dreams and beats them up.
Luffy, Zoro and Nami meet the man who is later revealed to be Blackbeard. They leave Mock Town, and get into a fight with Masira's brother Shōjo, another salvage monkey.
The Straw Hats meet with Montblanc Cricket on another part of Jaya; Cricket is a descendant of Montblanc Noland, an infamous "liar" who told of a gold city on Jaya, and Cricket was outcasted for looking for artifacts of the gold city. He may be the only person who knows how to get to Skypiea.
Cricket explains how the Straw Hats can ride a dangerous vertical current called the Knock-Up Stream to get to Skypeia. However, they first have to catch a southbird to point them toward the point where the stream will erupt from the ocean.
While the Straw Hats are looking for a Southbird, Bellamy and his crew attack Cricket's house, and steal the gold artifacts he'd collected over the years from his salvage work. When the Straw Hats return and see what happened, Luffy decides to take a side trip back to Mock Town.
Luffy takes out Bellamy with a single punch. Meanwhile, the world government heads are concerned over Whitebeard, Shanks, and Luffy. The marines try to decide who will replace Crocodile as a Shichibukai - one of Blackbeard's crew shows up uninvited and nominates his captain.
The Going Merry is refitted by Masira and Shōjo to be more flight capable, and the Straw Hats catch a ride on the Knock-Up Stream for Skypeia.
The Straw Hats have some problems with the local justice enforcer force called "The White Berets."
Before they can leave Chopper, Robin, Nami and Zorro are abducted by a giant shrimp. Luffy, Sanji and Usoppe go after them to the upper yard
Conis leads Luffy, Usopp, and Sanji to a boat to get to Upper Yard, but she tells them it is a trap and almost gets hit by "Heaven's Judgment".
Luffy, Usopp and Sanji finally enter Upper Yard, only to find out that the whole road is trapped heavily, but at last they arrive at the Ordeal Gates. Meanwhile Robin, Zoro, and Nami go out to explore Upper Yard while Chopper stays behind to guard the ship.
Luffy, Sanji, and Usopp enter the Ordeal of Balls gate and encounter the Priest Satori.
Usopp, Sanji and Luffy fight Satori, but the power of Mantra seems to be too strong.
Chopper, threatened by priest Shura, blows the whistle for Gan Fall to come, but before he can arrive, Priest Shura assaults Chopper and begins destroying the Going Merry.
Satori is defeated by Luffy and Sanji. Mainwhile has Gan Fall been defeated and Chopper jumps in the water to rescue him.
Chopper is saved by a bunch of giant Southbirds, who tell him that Gan Fall was actually God. Nami, Zoro and Robin discover the reason why Upper Yard is a soil island: It was once part of Jaya, and this is the part that Liar Norland saw. Meanwhile the Shandians attack Upper Yard.
After befriending a wolf pack, Gan Fall tells the crew a little more about the history of Upper Yard.
Eneru takes away the limitations of the priests. Also, Usopp witnesses a mysterious person fixing the ship; the next day Merry is found to be back to her original form. After getting her off the altar, the pirates plan out their course of action.
A giant python makes Luffy, Robin, Chopper and Zoro split while going to the ruins at the south.
Luffy fights Wyper, but after some time, he falls into some underground ruins. Meanwhile, Eneru appears on the Going Merry and after telling that his true goal was the City of Gold, he takes out both Usopp and Sanji; then he vanishes and leaves Satori's brothers: Hotori and Kotori to avenge him.
Priest Ohm appears and starts fighting everyone.
Ohm makes matters worse, creating a barbed wire cage around the area. Laki is knocked out by Eneru, and Nami, Aisa, and Gan Fall find out why the python was rampaging so much.
Zoro finally defeats Priest Ohm with his 108 Caliber Phoenix technique. Meanwhile Pagaya and Conis hear the terrible truth about the goal of Eneru: to eradicate every person in the sky.