Brain tries to get all the people off Earth onto his paper mache creation, Chia Earth.
Using Johannes Gutenberg printing press, the Brain make a series of collectible trading cards.
A successful modern artist is born and it's Pinky, trying to help fund Brain's new plan.
Brain hopes his inter-galactic pen pal, Zalgar, will help him take over the world. But it turns out Zalgar likes to snack on brains.
Pinky and Brain get sealed in an Egyptian pyramid where a mummy is lurking about.
Brain gets a group of men to steal money from the rich (ala Robin Hood) to pay for his new plot.
Pinky writes a letter to the newspaper criticizing the comic strip "The Family Circus". His letter, however, is misunderstood as a political statement that thrusts him to a spotlight that leads him to the Presidency of the United States. Pinky's administration, however, must deal with a scandal when the Brain's plans to take over the world are made public.
Brain makes a tearjerker movie to make the world sad enough to make him leader.
Animal rights activist think Pink and the Brain are monkeys and release them into the jungle after taking them out of Acme Labs. The pair try to make it back home, but run into the Brain's old enemy Snowball.
Brain tries to discover what makes the legendary Sampson so strong.
When Brain comes to the conclusion he no longer wants to take over the world, he decides to help others who had his problem and the first one to be helped is Pinky.
Pinky and Brain stumble upon a super powered baby, who happened to arrive from an exploding alien world.
Pinky and Brain have to brave a virtual reality maze to find a microchip crucial to Brain's new plot.
The mice's future selves arrive in the lab, sending them on a roller coaster ride through time to find a world domination kit.
Pinky and Brain's DNA get merged during a cloning experiment, creating a new mouse.
Pinky and Brain put together a basketball team as part of their next plan, but the fame may be swelling Brain's head.