Brothers Sam and Dean Winchester were raised to be soldiers. Now, as they join other hunters traveling the country to track down the evil fugitives from Hell hiding in the darkest corners of America, they must also battle their internal demons.
Bracing themselves for the possibility of an apocalyptic war, Sam (Jared Padalecki) and Dean (Jensen Ackles) realize they have an enormous task of hunting down the hundreds of demons that escaped from the Devil's Gate.
With only a year left to live, Dean decides to live life to the fullest and exhibits a carefree attitude that troubles Sam, who is trying to find a loophole in the deal. Bobby (Jim Beaver) tells the brothers about a sighting in Nebraska that turns out to be seven demons that are the actual manifestations of the Seven Deadly Sins.
Kim Manners directed the episode written by Eric Kripke.
Dean (Jensen Ackles) pressures Sam (Jared Padalecki) into visiting Cicero, Indiana, so he can visit an old flame named Lisa (guest star Cindy Sampson), he had a tryst nine years ago. However, Dean is stunned when he meets not only Lisa again, but also her 8-year old son Ben (guest star Nicholas Elias), who bears a striking resemblance to him.
However, Ben soon goes missing and Sam and Dean discover that a Changeling, a demonic parasite, is snatching kids from the small town and assuming their form. Meanwhile, Ruby (Katie Cassidy) makes contact with Sam and reveals some startling information about his mom.
Phil Sgriccia directed the episode written by Sera Gamble.
Sam (Jared Padalecki) and Dean (Jensen Ackles) answer a call on their dad's old cell phone, alerting them someone has broken into John's secret storage room in New York. They discover a cursed rabbit's foot has been stolen and call Bobby (Jim Beaver) for help.
He advises them to beware of the foot because anyone who touches it will receive an extreme amount of good luck, but once the foot is lost that person will die. Unfortunately, Sam has already handled the foot, which causes an overjoyed Dean to buy lottery tickets, but a female thief (Lauren Cohan) steals it from Sam causing his luck to plummet and putting his life in danger.
Bob Singer directed the episode written by Ben Edlund.
Sam (Jared Padalecki) and Dean (Jensen Ackles) investigate a rash of violent deaths in Elizabethville, Ohio, a once-sleepy town that has been turned into a haven for gamblers and drinkers.
Dean discovers demons have infiltrated Elizabethville and are using their powers of persuasion to make the townspeople succumb to their basic instincts. Meanwhile, Ruby (Katie Cassidy) helps Bobby (Jim Beaver) rebuild the Colt from scratch and stuns him with some news.
Charles Beeson directed the episode written by Robert Singer & Jeremy Carver.
Sam (Jared Padalecki) and Dean (Jensen Ackles) investigate a small town that has been plagued by a number of strange murders that resemble fairy tales, such as Little Red Riding Hood, Snow White and Hansel and Gretel.
Meanwhile, Sam summons the Crossroad Demon (guest star Sandra McCoy) and threatens to kill her with the newly rebuilt Colt unless she releases Dean from his deal.
Mike Rohl directed the episode written by Cathryn Humphris.
Sam (Jared Padalecki) and Dean (Jensen Ackles) investigate the mysterious demise of drowned victims who were nowhere near the water at the time of their death.
The brothers learn each of the victims saw a ghost ship shortly before they died.
Upon investigation, they cross paths with Bela (Lauren Cohan), who is being paid handsomely by one of the murder victim's family members to solve the case.
Sam and Dean warn her to stay out of their way, but she has other plans.
Cliff Bole directed the episode written by Laurence Andries.
Sam (Jared Padalecki) and Dean (Jensen Ackles) capture a female vampire named Lucy (guest star Mercedes McNab) who claims to have no knowledge of how she became a vampire. The guys discover Dixon (guest star Matthew Humphreys), a male vampire, is giving out human blood to unsuspecting females in bars, offering it up as the "latest drug" and turning them all into vampires.
Meanwhile, Gordon (guest star Sterling K. Brown) escapes from jail and goes after Sam. However, Dixon intercepts Gordon and turns him into a vampire, which makes Gordon more powerful than before and a much bigger threat to Sam.
Kim Manners directed the episode written by Sera Gamble.
In this Christmas-themed episode, Sam and Dean follow the trail of an "anti-Santa" that abducts its victims by using their chimneys. Dean tries to get Sam to celebrate Christmas like they used to but Sam doesn't want to accept that it could be the last one they'll spend together.
Sam (Jared Padalecki) and Dean (Jensen Ackles) travel to Sturbridge, Massachusetts, and discover a coven of witches that has killed two people. Ruby (Katie Cassidy) warns the brothers to stay away as the demon controlling these witches is very powerful and will surely kill them. Ignoring her plea, Sam and Dean go in after the coven and confront the head witch, who reveals Ruby's past.
Sam (Jared Padalecki) and Dean (Jensen Ackles) race to Bobby's (guest star Jim Beaver) side after he lapses into a coma and can't be awakened. While unconscious, Bobby battles his personal demons and the reason he became a hunter is revealed.
Sam and Dean discover someone poisoned Bobby with a potion that will kill him if he doesn't wake soon. When the brothers decide to take the potion themselves to enter Bobby's dream in order to save him, they come face to face with their own personal nightmares.
Steve Boyum directed the episode written by Cathryn Humphris.
Sam (Jared Padalecki) and Dean (Jensen Ackles) investigate the disappearance of a man who went missing at a tourist location. While searching the site, Dean is shot and killed by the owner. Sam is devastated but stunned when he wakes up the next morning to find Dean alive and well. As the day unfolds, Sam realizes he is re-living the previous day and tries to prevent Dean’s death, but to no avail. Dean dies again and Sam must learn to live life without his brother by his side.
An episode reminiscent of the film Groundhog Day, which finds the boys repeating the same day over and over again. Eric Kripke reveals, "Sam basically wakes up every day and it's the same day and Dean dies at the end of every single day. It's actually quite funny."
Sam (Jared Padalecki) and Dean (Jensen Ackles) break into Bela’s (Lauren Cohan) apartment in order to get the Colt back, but she has tipped off Agent Henricksen (guest star C. Malik Whitfield) about their whereabouts and they are arrested. While Sam and Dean are locked in a cell in Colorado, a demon breaks in and kills some of the sheriff’s men and possesses Henricksen. After the guys vanquish the demon, the FBI agent realizes they were telling the truth and prepares to release them, but Ruby (guest star Katie Cassidy) shows up to a warn Sam and Dean that the jailhouse is surrounded by a band of demons with a powerful new leader who wants Sam dead.
Kim Manners directed the episode written by Sera Gamble.
In "Ghostfacers!," written by Ben Edlund and directed by Phil Sgriccia, we reconnect with Ed Zeddmore (guest star A.J. Buckley) and Harry Spengler (guest star Travis Wester), two amateur ghost hunters whom we first met in Season One when they showed up to "work" the same case that Sam & Dean Winchester were on in the "Hell House" episode. Now they're back with a crew of family & friends to shoot a pilot for a reality show called...you guessed it..."Ghostfacers!," in which Sam & Dean end up as reluctant guest stars. "Ghostfacers!" is also interesting in that the episode was shot almost entirely by the actors portaying the Ghostfacers themselves, using handheld and mounted HD cameras to capture the "reality" action in a 360 degree format.
Dean (Jensen Ackles) is stunned after he receives a phone call from his dad (guest star Jeffrey Dean Morgan) who tells him he has a solution to get Dean out of his deal.
Sam (Jared Padalecki) and Dean fight because Sam is skeptical that it is really John on the other end of the phone and warns Dean not to listen to him but Dean disagrees and sets off on his own path to follow his father's orders.
As time runs out for Dean (Jensen Ackles), Sam (Jared Padalecki) convinces him to head to Eerie, Pennsylvania to investigate a possible zombie case.
Instead, they discover Doc Benton (guest star Billy Drago), a real-life doctor who, in 1816, abandoned his medical practice to follow his obsession with finding the key to eternal life by drugging people and stealing their vital organs.
Meanwhile, Bobby (Jim Beaver) finds out where Bela (Lauren Cohan) is hiding, and Dean heads out to confront her, leaving Sam behind to deal with the good doctor. Dean and Bela battle it out for the last time, and Dean leaves Bela in a desperate, and possibly fatal, position.
Charles Beeson directed the episode written by Sera Gamble.
It's 30 hours before Dean's (Jensen Ackles) deal with the crossroads demon is up and Dean, Sam (Jared Padalecki) and Bobby (Jim Beaver) are searching for Lilith, who holds the contract. They discover her location and Sam summons Ruby (Katie Cassidy) for help despite Dean's protests. Ruby warns them they aren't ready to fight Lilith yet but they steal her knife and depart for New Harmony, Indiana.
In a battle to the death, Sam, Dean and Bobby take on Lilith and all her demons in a last ditch effort to save Dean's life.