The thrilling and terrifying journey of the Winchester Brothers continues with the sixth season. Sam (Jared Padalecki) and Dean (Jensen Ackles) spent their lives on the road, battling every kind of supernatural threat. And over the years, after dozens of bloody adventures, they finally closed in on their dark destiny. Sam and Dean learned they were to be important and prophesied participants in the Apocalypse. Together with the help of their friends-father-figure Bobby and fallen Angel Castiel- they managed to avert the End and defeat Destiny itself.
It's a year later and Dean (Jensen Ackles) has given up hunting and is living with Lisa (guest star Cindy Sampson) and her son Ben (guest star Nicholas Elia). Mysteriously freed from his cage in hell, Sam (Jared Padalecki) finds Dean and tells him he needs to rejoin the fight and introduces Dean to a world-a family-he never even knew existed: the Campbells, his mother's family, lead by none other than their Grandfather Samuel (Pileggi). Phil Sgrricia directed the episode written by Sera Gamble.
Sam (Jared Padalecki) investigates a case about missing babies whose parents are being murdered. At one of the crime scenes, he discovers a baby that was left behind and calls Dean (Jensen Ackles) for help. Reluctant to leave Lisa (guest star Cindy Sampson) and Ben (guest star Nicholas Elia), Dean finally agrees to meet Sam and surprises his brother with how parental he has become. The brothers take the baby to Samuel (Mitch Pileggi), who decides to raise it as a hunter, which infuriates Dean. However, before they can decide the baby’s future, a shape-shifter breaks in and attempts to kidnap the baby. John Showalter directed the episode written by Adam Glass.
Sam (Jared Padalecki) and Dean (Jensen Ackles) call Castiel (Misha Collins) for help when they investigate a case about several dead police officers who seem to have been killed by the plagues of Egypt. Castiel confirms the staff of Moses was used to kill the cops and tells Sam and Dean that Heaven is in a state of chaos and God’s weapons have been stolen. The three head off to find the thief and come face to face with an old enemy.
After Bobby (Jim Beaver) discovers Crowley (Mark Sheppard) has no intentions of returning Bobby’s soul, the hunter takes matters into his own hands. He calls on Sam (Jared Padalecki) and Dean (Jensen Ackles) for help after he unearths one of Crowley’s deepest secrets. Meanwhile, Sam and Dean learn what Bobby does all day when they are not around. Jensen Ackles directed the episode written by Andrew Dabb & Daniel Loflin.
After a group of young girls go missing, Sam (Jared Padalecki) and Dean (Jensen Ackles) realize that a group of vampires have taken up residence in the small town. After a fight with two of the blood-suckers, Dean is bitten and turns into a vampire. Samuel (guest star Mitch Pileggi) tells Dean he can change him back but he’d have to get the blood of the vampire who turned him. Dean infiltrates the nest and runs into the Alpha.
Sam (Jared Padalecki) and Dean (Jensen Ackles) investigate a series of suicides and discover the victims were being told brutal truths that drove them crazy. They find out someone is invoking the Goddess of Truth, Veritas, forcing people to be cruelly honest against their will and Dean is the next victim. Dean is forced to tell Sam the truth about how he feels about his return from Hell.
Dean (Jensen Ackles) becomes suspicious of Samuel’s (guest star Mitch Pileggi) motives, but Sam isn’t sold on the idea that their grandfather is doing anything wrong. The brothers go along on a hunt with Samuel and the other Campbells, but things go terribly awry.
Dean (Jensen Ackles) and Sam (Jared Padalecki) investigate what seems to be a werewolf killing but turns out to be a skinwalker (guest star Andrew Rothenberg) posing as a family dog who is taking revenge on his owner’s enemies. After capturing the dog, he turns human and tells Sam and Dean that an Alpha skinwalker has created many sleeper cells that will rise on his command and kill their families. The only way to stop the mass murders is to find and kill the Alpha. Phil Sgriccia directed the episode written by Adam Glass.
While Sam (Jared Padalecki) and Dean (Jensen Ackles) are investigating a UFO sighting, Dean is abducted from a crop circle. However, when he awakens, he discovers he isn’t dealing with aliens, but fairies! Unfortunately, only Dean can see the fairy that keeps attacking him which makes tracing and stopping them difficult. The brothers become even more perplexed when Sam’s investigation leads them to a world full of elves, gnomes and a leprechaun. John Showalter directed the episode written by Ben Edlund.
Meg (guest star Rachel Miner) kidnaps Sam (Jared Padalecki) and Dean (Jensen Ackles) and tries to force them to tell her where Crowley (guest star Mark A. Sheppard) is hiding. Sam makes her a deal – they will help her find Crowley if she promises to torture him for information about how to get Sam’s soul back. Castiel (Misha Collins) joins the fight but finds it difficult to work with Meg. Robert Singer directed the episode written by Brett Matthews with story by Brett Matthews & Jenny Klein.
Dean (Jensen Ackles) seeks out Death (guest star Julian Richings) to help get Sam's (Jared Padalecki) soul back. Death tells Dean he will help Sam if Dean will agree to act as Death for 24 hours. Meanwhile, Sam decides he doesn't want his soul back and asks Balthazar (guest star Sebastian Roché) for a protective spell to keep his soul out of his body. Balthazar tells Sam he needs the blood of his father for the spell to work and since John Winchester is dead, Sam decides Bobby (Jim Beaver) is the next best thing. Mike Rohl directed the episode written by Sera Gamble & Robert Singer.
Dean (Jensen Ackles) and Bobby (Jim Beaver) anxiously wait for Sam (Jared Padalecki) to wake up to see if Death (guest star Julian Richings) was able to restore his soul without causing Sam to lose his mind. Meanwhile, Dean and Bobby investigate a disappearance of virgins and discover dragons are behind the kidnappings. Bobby sends Dean to a doctor who owns the only weapon in the world that can slay a dragon, but Dean must prove himself worthy enough to take it. Phil Sgriccia directed the episode written by Adam Glass.
Sam (Jared Padalecki) starts to have flashbacks to a case he worked on with Samuel (guest star Mitch Pileggi) before he reconnected with Dean (Jensen Ackles). Sam receives a mysterious text with coordinates to a small town, so the brothers decide to investigate. Dean is surprised when the townspeople start telling him some of the things Sam did while he lived there. David Barrett directed the episode written by Andrew Dabb & Daniel Loflin.
Ben calls Dean and tells him Lisa is in trouble. Dean leaves Sam to investigate a case alone and rushes home to rescue Lisa, however, he's not prepared for what meets him at the door. Meanwhile, Sam discovers the men that were murdered were all a part of a cruel practical joke played on a female co-worker who went missing.
Raphael (guest star Lanette Ware) launches an attack on Castiel (Misha Collins) and his allies, sending a particularly frightening angelic hitman (guest star Carlos Sanz) after Balthazar (guest star Sebastian Roche), Sam (Jared Padalecki) and Dean (Jensen Ackles). In an effort to protect the brothers, Balthazar sends them to an alternate universe where they are the stars of a TV show called “Supernatural” and they are actors named “Jensen Ackles” and “Jared Padalecki.” The brothers are confused when Castiel appears to be a tweet-happy actor named Misha Collins and Sam is married to Ruby (Genevieve Cortese). Charles Beeson directed the episode written by Ben Edlund.
Sam (Jared Padalecki), Dean (Jensen Ackles) and Bobby (Jim Beaver) set out in search of The Mother of All’s latest monster. While investigating, they run into Samuel (guest star Mitch Pileggi) and Gwen (guest star Jessica Heafey), who are also hunting the creature. Samuel and Bobby get into a heated fight about how to handle the case.
After Balthazar (guest star Sebastian Roche) changes history and keeps the Titanic from sinking, Fate (guest star Katie Walder) intervenes and begins killing those that would have died on the ship. Castiel (Misha Collins) tells Sam (Jared Padalecki) and Dean (Jensen Ackles) that Fate is very upset with the two of them and the only way they can stay alive is to kill her. Phil Sgriccia directed the episode written by Eric Charmelo & Nicole Snyder.
While searching for a way to defeat Eve, Dean stumbles upon Samuel Colt’s (guest star Sam Hennings) journal in the Campbell library. Realizing Samuel might have the answer to their problems, Sam and Dean ask Castiel (Misha Collins) to send them back in time so they can meet the man himself. While Sam is a bit reluctant to time travel, Dean is beside himself with excitement to return to the Wild, Wild West. Guy Bee directed the episode written by Andrew Dabb & Daniel Loflin with story by Andrew Dabb, Daniel Loflin & Jackson Stewart.
Sam (Jared Padalecki), Dean (Jensen Ackles), Bobby (Jim Beaver) and Castiel (Misha Collins) track Eve (guest star Julia Maxwell) to a small town in Oregon. The guys discover the townspeople have been converted to demons, but surprisingly, they all appear to be dying. When they finally do meet Eve, she decides to torture the brothers by bringing back their mother, Mary Winchester (guest star Samantha Smith), as a demon.
Castiel (Misha Collins) tells Sam (Jared Padalecki), Dean (Jensen Ackles) and Bobby (Jim Beaver) about the war in Heaven and how he and Raphael became enemies. Bobby believes Castiel is hiding something, but Dean refuses to believe it.
A demon kidnaps Ben (guest star Nicholas Elia) and Lisa (guest star Cindy Sampson) to get to Dean (Jensen Ackles). Sam (Jared Padalecki) and Dean are forced to join with an unlikely ally to free them.
The wall comes down in Sam’s (Jared Padalecki) head and all hell breaks loose. Dean (Jensen Ackles) and Bobby (Jim Beaver) are, for once, at a total loss on how to help him and are forced to stand by and do nothing while Sam breaks. The battle for heaven comes to a head.