The four members of Rescue Force Sigma-17 emerge and are greeted by the Autobot leader Optimus Prime, who assigns them to work with the Burns family on an island. While the four are supposed to respond to every command the humans give them, they get fed up with it and are tempted to leave Earth. This changes when an animatronic dinosaur attacks the island.
While Chase and Chief Burns pursue an out-of-control robo-landscaper through Griffin Rock, Cody Burns reports that the rest of the team might be delayed, as his siblings are having trouble coming to terms with the fact that their rescue vehicles are alien robots. A volcano suddenly threatens the island of Griffin Rock, sending the Rescue Bots and Burns family into action. The group has to put aside their differences and work together in order to save the island.
Dani gives Blades a new scoop claw in order to take a more integral part of the rescue missions. However, the pair manage to complete subsequent missions by themselves, leaving the others out of the action. Kade and Graham argue with Dani about this, while the Rescue Bots threaten to remove the scoop claw from Blades. Blades goes on patrol with Dani and Cody, but are struck by lightning during a storm. The rest of the group settle their differences aside and head out to save them.
After Heatwave grows fed up with maintaining his robot disguise, Chase, Blades, and Boulder must battle hundreds of jagged claws when an enormous swarm of snapping lobsters overruns the annual Griffin Rock summer festival.
Huxley Prescott is determined to dig up scoop about aliens invading planet earth. However he finds that his enthusiasm could indeed put many people in danger. The Rescue Bots also question their disguise to sustain that 'robot' image for the public instead of revealing their true identity.
When Cody super-charges his go-kart to help in the team's rescue missions, he accidentally unleashes a swarm of futuristic nanites.
The Rescue Bots are enlisted to watch after Doc Greene's Robo-Baby.
Boulder decides that the team needs an animal mascot, but maybe a zoo isn't the best place to find one.
The Burns Family and the Rescue Bots have to stop a snow storm in July when a weather machine goes haywire.
A shark targeting high-tech ocean equipment is spotted off the Griffin Rock shore.
An intruder hacks into Griffin Rock's central computer and wreaks havoc.
A scientist tries to replace the team with a new invention, leaving everyone out of the action.
Cody looks for proof that the new scientist's invention is really a villainous plan.
The Rescue Bots are accidentally shrunk and the Burns family must work without their partners.
The Burns family learns of the Griffin Rock Triangle and watch film reels about said phenomenon that are taped by Professor Anna Baranova. They embark on an underwater investigation and stumble upon the Midgard, a laboratory that has been trapped near an ocean trench from a methane explosion. They scope the laboratory's interior, where they find Baranova who has been inside for 28 years. Baranova initially refuses to leave her new home, but, after Cody's motivational statements, decides to detonate a bomb to her laboratory and move back to Griffin Rock.
When Heatwave leads his team into a lethal situation, against Chief Burn's orders, Chase must find a way to help them, while following the rules.
The Rescue Bots and Cody get separated from the Burns family during a thunderstorm, and drift to a remote island. There, the team learns how to survive like pioneers. They also locate a pirate ship, and inside lays a bell that was stolen from Griffin Rock by pirates about 200 years ago. The next morning, the team departs the island with the bell on a pirate boat. On their way back to Griffin Rock, they are able to locate and reunite with the family.
The Rescue Bots and the Burns family investigate a meteor that has landed on Wayward Island. Bumblebee arrives and joins with the group, while receiving remote assistance from Optimus Prime. When the particle components emanated by the meteor immobilize the Autobots and render them mute, the Burns create an antidote that reverses the effects.
Doc Greene acquires a slimy green compound, the "Squilsh", from Mars, and summons it to life with a mild electric shock. The Squilsh devours anything in its path and grows progressively bigger after each meal, and it eventually rampages through Griffin Rock. Graham and Boulder apply their engineering knowledge towards efforts of defeating the creature.
Doc Greene accidentally releases a swarm of bugs from the town's museum, the Hall of Inspiration. As the bugs disperse throughout Griffin Rock, the citizens mysteriously disappear and are teleported to an underground cavern. Cody and Frankie contact Professor Anna Baranova, who explains that these bugs are called "tracers", programmed to protect the town's population from a forthcoming cataclysm. The location of the cavern, however, has never been disclosed historically, so the Rescue Bots are forced to figure out such location in order to save the fettered citizens.
The Burns receive mass calls of ghostly spirits supposedly haunting Griffin Rock. In an analysis conducted by Frankie, these supposed phantoms are merely holograms depicting the town's pioneers. These holograms were also used as a ruse for two escaped convicts to engage in criminal actions unnoticed. Pioneer Charlotte Wayne (also known as the Lady of Griffin Rock), however, is witnessed to be a potentially real ghost, because she has never been registered into the town museum's database, so there exists no corresponding hologram for her.
The kids are covertly planning a surprise birthday party for their father. Chief Burns tells them he is heading to the docks, but actually takes a trip to the bakery for a cake, as a present for his family, thinking that they forgot his birthday. Chase discovers this to be a lie and is confounded by this. While setting up the party back home, the kids and the other Rescue Bots realize that Chase and Chief Burns are missing, and search the entire town. Eventually they discover the two trapped inside an underground mine, and save them from the flooding water and falling rocks.
Seismic waves shake Griffin Rock, but they are artificial and caused by a reverberating woofer hidden underground. Such loudspeaker is inadvertently connected remotely to Doc Greene's jukebox, where Doc Greene is practicing his dance moves. Meanwhile, Frankie creates a music video that includes footage of the Rescue Bots. Suspicious, she follows them into an underground tunnel during their mission to remove the loudspeaker inside, and attempts to converse with Heatwave. When the rocks are falling from the tunnel ceiling, Heatwave breaks from his "robot" character to save her, during which she finally learns of the Rescue Bot's secret.
Doc Greene invents a repulsor badge that allows the wearer to be invincible. Cody uses it to participate more on the front lines, in missions with the rest of his family, against Chief Burns concern of his safety. His superhero status, however, is halted when his repulsor badge is overloaded and projects a nonstop field, enclosing him inside. Boulder uses neutralizing gloves, also invented by Doc Greene, to bypass the repulsive field and successfully remove the badge from Cody, shortly before it detonates.
Doc Greene calls the entire Burns family to demonstrate testing of an abandoned time machine. He sends his helper bot Dither into the time warp, which takes the Rescue Bots, Cody, and Frankie along with them. They are transported into the year 1939, with no discernible method of returning to the present. Optimus Prime—informed by Chief Burns of the dilemma—and Bumblebee also travel back to 1939, to provide their Energon (the predominant energy of the Autobots) needed to repower the machine. All the time travelers manage to return to the present, but much to their devastation discover that the timeline has been altered, as they had inadvertently left Dither behind in the past.
The present-day town of Griffin Rock, renamed "Moropolis", is ruled by Doctor Morocco and his MorBots. The protagonists scourge the town and arrive at the Hall of Inspiration, where they encounter Chief Burns, who, despite having no memories of them, takes them to his fire station. Morocco calls upon an entire armada of his MorBots to launch a mass attack. The Burns family retaliate with their Mobile Headquarters (MHQ) vehicle; the Autobots partake in smashing the MorBots. The group returns to the past with the MHQ, where Heatwave reclaims Dither, and travel back to the present day, with their original timeline restored.