The battle for the student body begins. Toni Collette returns for a new season of United States of Tara, the Showtime Original Series from executive producer Steven Spielberg. When Tara goes back to college her alters turn the school, and her family, upside down.
Max is worried when Tara returns to college to finish her college degree. Meanwhile, Charmaine with a baby on the way is avoiding a commitment to Neil, Kate tries to figure out a plan for her future and Marshall and Lionel sign up for a filmmaking class.
Her psychology professor humiliates Tara when she transitions in his class. Meanwhile, Kate considers giving English lessons in Japan and Max gets a business offer.
Charmaine gets into troubles after Tara transitions again and Max has to pay his eccentric mother a visit when he needs her approval.
Charmaine and Tara are taken to the hospital and Tara meets her alters to make a deal. In the meantime, Marshall, Noah and Lionel find use for Charmaine's hous and Kate makes a fool of herself.
Tara tries to drop her Abnormal Psychology class but instead receives an intriguing pitch from her instructor, Dr. Hattaras; Charmaine and Neil find parenthood a struggle but still refuse Tara's help; Max finds himself at odds with his boss at his new job; Kate prepares for flight attendant training; Lionel catches Marshall with Noah, jeopardizing their student film project.
Tara seems to be making progress with her new contract but Dr. Hattaras discovers something disturbing in a tape from one her therapy sessions; much to the sisters' chagrin, Neil invites Tara and Charmaine's mother to visit her grandchild; Max is unhappy at his new job but can't talk to Tara about it; Kate is surprised when a handsome flyer rebuffs her flirting.
Max is delighted by Tara's suggestion that he reunite his rock band, Beaverlamp; Tara is turned away from further sessions by a strangely depressed Dr. Hattaras; Kate connects with frequent flyer Evan; Marshall and Noah stage a tense, revealing interview with Max for their film festival project.
A scare at a local corn maze leaves Tara shaken, and she later reveals a new alter that threatens Charmaine's baby and shows up at Dr. Hattaras' office as Alice, renewing his interest in her case; Kate escorts Max and Marshall to New York, where she introduces them to Evan and his unruly son; Charmaine meets a "fierce mommy" at a spa.
Dr. Hattaras and Tara seek the help of another professional (guest star Robert Picardo) to deal with her violent new alter Bryce; Marshall is confused when his short film about Max clearly hurts his father's feelings; Charmaine hangs out with a group of "chic moms;" Kate continues her long distance relationship with Evan despite the interference of his son.
Max and Marshall return home to disturbing news about Dr. Hattaras and Lionel. Tara hides the existence of her new alter. Neil lands a job that will require him to move to Texas.
Tara's other alters disappear, leaving only Bryce. Marshall moves in with his grandmother. Kate spends more time in St. Louis with Evan. Neil asks Charmaine to move to Texas.
Tara and Max go to Boston for help from an expert. Neil and Charmaine prepare to move to Houston. Kate receives a life-changing proposal. Marshall considers his future.