Alyssa Milano will star as the lead in ABC's untitled Rina Mimoun drama pilot. According to The Hollywood Reporter, the show centers on a successful Atlanta lawyer (Milano) who returns to her messy family in Savannah, Ga., with her newborn son; Mary Steenburgen already has been cast as her mother.

Angie Harmon has signed on to star in another ABC drama pilot, Women's Murder Club; from 20th Century Fox TV, it centers on homicide inspector Lindsay Boxer (Harmon), who teams with her three girlfriends to solve murder cases.

Brian Austin Green, Jessica Capshaw and Vanessa Lengies have landed three of the four leads in CBS' untitled Kohan/Mutchnick comedy pilot. The show is about two friends and writing partners, one straight and one gay (Green), and the women working with them (Capshaw, Lengies).

Carlos Jacott and Samantha Bee will star in Fox's comedy pilot, Two Families. The show revolves around two sets of adult siblings who didn't know they shared the same father (Beau Bridges). Jacott and Bee will play twins from one of the two families.

Johnny Messner has landed a lead role in ABC's drama pilot, Judy's Got a Gun; it's a procedural drama about Judy Lemen (Louise Lombard), a detective and a single mom. Messner will play a recent transfer to the police department, a hothead who shares a spark of attraction with Judy.

Danny Comden has been cast in ABC's comedy pilot, The Call. The show revolves around a group of unconventional paramedics, one played by Comden.

Liz Vassey is set to co-star on Fox's drama pilot, The Cure; it centers on a group searching for miracle cures. Vassey will play a top biotech scientist.

Bruce McGill has joined NBC's comedy pilot Area 52, an office comedy set at a secret location in the Nevada desert; McGill will play Gen. Keller, a military journeyman.

Will Yun Lee has come on board NBC's, The Bionic Woman. It's a re-imagination of the 1970s series and stars Michelle Ryan in the title role; Lee will play a field leader.

In other pilot-casting news, Molly Stanton is set to star in Fox's untitled Liz Meriwether comedy pilot. Ben Feldman has joined Fox's drama pilot, Them.

Ava Gaudet and Stephen Rannazzisi have joined ABC's comedy pilot, See Jayne Run. Aaron Paul has been tapped to star opposite Brian Cranston in AMC's pilot, Breaking Bad

T.J. Miller has come aboard ABC's comedy pilot, Carpoolers