Anaconda 2:Dark Horizons has gotten word from the set of the Anaconda sequel:

The pre-production crew is creating an artificial lake right now which they have to fill back in after shooting is done. There is no J-Lo (but hey, there is always the possibilities of secret cameos), the cast so far is pretty unknown, but in other movies right now, so they hope those actors are better known when the movie comes out. Word is that the movie is set in Borneo, interestingly there are no Anaconda's in Borneo, so plot wise who knows where in the hell they're going.

In addition, Movie Hole has gotten word about the storyline:

"The story is essentially a good old fashioned jungle adventure about a scientific expedition (the charismatic but unethical scientist, his greedy and often cowardly business partner, the good and highly ethical girl scientist named 'Sam,' and the handsome but crusty and always brave jungle guide, her unlikely romantic interest, who apparently now also has a pet monkey... and why not?) that travels to the darkest jungles of Borneo (although they are now filming in Fiji) in pursuit of a rare black orchid that blooms only once every seven years and just might, maybe, could hold the secret to immortality (or at least living a lot longer) and is therefore worth more than Viagra to the pharmaceutical company sponsoring the expedition. When the snakes aren't present, human greed, ambition and murder hold the stage. And when the snakes start showing up, well, what the black orchid is really good for, it would seem, is turning big snakes into really, really huge snakes since, as we all know, Anacondas never stop growing, and the longer they live, the bigger they get and the more people they can eat in this sort of old fashioned jungle adventure."
Brian B.