Later this week, Marvel's massive Phase 3 blockbuster Captain America: Civil War will cross $300 million domestically while passing the $1 billion mark at the global box office, after two impressive weekends in release. But it's possible that it may fall out of the top spot this weekend. The superhero adventure faces its biggest threat to the crown thus far, going up against three highly-anticipated new releases, Sony's The Angry Birds Movie, Universal's Neighbors 2: Sorority Rising and Warner Bros.' The Nice Guys. While it all depends on how much Marvel's Civil War drops in its third frame, we're predicting that The Angry Birds Movie will come out on top.

According to Box Office Mojo, The Angry Birds Movie will open in more than 3,700 theaters, which is still roughly 500 theaters fewer than Captain America's 4,226-theater rollout, but it's the biggest debut Cap and The Avengers have faced thus far. Neighbors 2: Sorority Rising is expected to debut in more than 3,000 theaters, while The Nice Guys is set to debut in just over 2,800 theaters. The Angry Birds has been getting mixed reviews thus far, with a 56% rating on Rotten Tomatoes, while its competitors have been faring much better, with Neighbors 2 posting a 66% rating and The Nice Guys scoring an impressive 95% rating on RT. Still, the family-friendly Angry Birds movie should have no trouble winning this weekend with a predicted $58 million.

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Last weekend, Captain America: Civil War dropped 59.5% to earn $72.6 million, which was still more than enough to win its second week in a row. We're guessing that Cap posts a slightly smaller decrease this weekend, taking in $42.1 million, dropping to second place. Neighbors 2 should be just behind this superhero adventure in third place with $40.4 million, which, if true, will come in significantly lower than its 2014 predecessor Neighbors, which opened with $49 million en route to a $150.1 million domestic take and $270.6 million worldwide, from just a $28 million budget. The Nice Guys should open in fourth place with a projected $15.5 million, as The Jungle Book rounds out the top 10 with $10.3 million.

In the 3D animated comedy, The Angry Birds Movie, we'll finally find out why the birds are so angry. The video game adaptation takes us to an island populated entirely by happy, flightless birds - or almost entirely. In this paradise, Red (Jason Sudeikis), a bird with a temper problem, speedy Chuck (Josh Gad), and the volatile Bomb (Danny McBride) have always been outsiders. But when the island is visited by mysterious green piggies, it's up to these unlikely outcasts to figure out what the pigs have planned. The voice cast is rounded out by Bill Hader, Maya Rudolph, Peter Dinklage, Keegan Michael Key, Kate McKinnon, Tony Hale, Ike Barinholtz and Sean Penn in his first animated voice role.

Neighbors 2 reunites fans with Mac (Seth Rogen) and Kelly Radner (Rose Byrne), who have a second baby on the way, and they are ready to make the final move into adulthood: the suburbs. But just as they thought they'd reclaimed the neighborhood and were safe to sell, they learn that the new occupants next door are a sorority even more out of control than Teddy (Zac Efron) and his brothers ever dreamed of being. Tired of their school's sexist, restrictive system, the unorthodox ladies of Kappa Nu have decided to start a house where they can do whatever the hell they want.

When Shelby (Chloe Moretz) and her sisters, Beth (Kiersey Clemons) and Nora (Beanie Feldstein), find the perfect place just off campus, they won't let the fact that it's located on a quiet street stand in their way of parties as epic as the guys throw. Forced to turn to the one ex-neighbor with the skills to bring down the new Greeks next door, the Radners-alongside best friends Jimmy (Ike Barinholtz) and Paula (Carla Gallo)-bring in charismatic Teddy as their secret weapon. If he can infiltrate the sorority and charm his way through it, the thirtysomethings will shutter the Kappas' home.

Set in 1970s Los Angeles, The Nice Guys follows down-on-his-luck private eye Holland March (Ryan Gosling) and hired enforcer Jackson Healy (Russell Crowe), who must work together to solve the case of a missing girl and the seemingly unrelated death of a porn star. During their investigation, they uncover a shocking conspiracy that reaches up to the highest circles of power. The supporting cast is rounded out by Beau Knapp, Keith David and Kim Basinger in this new comedy from director Shane Black (Iron Man 3).

Rounding out the top 10 this weekend will be Money Monster ($8.2 million), The Darkness ($3 million), Mother's Day ($2.4 million), Zootopia ($1.9 million) and The Huntsman: Winter's War ($1.4 million). Also opening in limited release this weekend is Oscilloscope Pictures' Ma ma, Sony Pictures Classics' Maggie's Plan, IFC's Weiner and FUNimation Films' Project Itoh - Harmony. We don't know for certain if any of these movies will be expanding to wider releases in the weeks to come, so stay tuned.

Looking ahead to next weekend, 20th Century Fox will debut the highly-anticipated superhero sequel X-Men: Apocalypse, alongside the Disney fairy tale sequel Alice Through the Looking Glass, which will be competing for the Memorial Day weekend crown. Also opening in limited release is Abramorama's As I AM: The Life and Times of DJ AM, Strand's Chevalier, FilmRise's Holy Hell, Adopt Films' The Idol, Magnolia's The Ones Below and Well Go USA's The Wailing. Be sure to check back on Sunday for the box office estimates, and again on Sunday for next week's predictions. Until then, take a look at our projections for the weekend of May 20.