It's been seven years since Tom Hanks' Robert Langdon appeared on the big screen with Angels & Demons. It seems that absence may not make the heart grow fonder in this case, since Tom Hanks' new Robert Langdon film Inferno opened in second place with a measly $15 million, behind repeat winner Boo! A Madea Halloween with $16.6 million. The opening weekend figure is the lowest in franchise history, and it remains to be seen whether this franchise will continue after this disappointing opening.

Box Office Mojo reports that Inferno opened in 3,576 theaters for a middling $4,195 per-screen average, which is by far the lowest box office debut in this franchise. The Da Vinci Code opened in 3,757 theaters back in May 2006 with an impressive opening weekend tally of $77 million. It would go on to earn $217.5 million domestically and $540.7 million internationally for a worldwide total of $758.2 million. It's 2009 follow-up Angels & Demons opened at $46.2 million domestically, going on to earn $133.3 million domestically, $352.5 million internationally and $485.9 million worldwide. Inferno wasn't a big hit with critics either, scoring just a 20% rating on Rotten Tomatoes.

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This new adventure finds the famous symbologist (Tom Hanks) on a trail of clues tied to the great Dante himself. When Langdon wakes up in an Italian hospital with amnesia, he teams up with Sienna Brooks (Felicity Jones), a doctor he hopes will help him recover his memories. Together, they race across Europe and against the clock to stop a madman from unleashing a global virus that would wipe out half of the world's population.

Academy Award winner Ron Howard returns to direct the latest bestseller in Dan Brown's billion-dollar Robert Langdon series, Inferno. The film's screenplay is written by David Koepp, based upon the novel by Dan Brown, with Brian Grazer and Ron Howard serving as the producers. The supporting cast for Inferno is rounded out by Irrfan Khan as Harry Sims, a.k.a. The Provost, Omar Sy as Christoph Bruder and Sidse Babett Knudsen as Dr. Elizabeth Sinskey, the head of the World Health Organization. Ben Foster is playing the villain Bertrand Zobrist, a scientist trying to unleash a global plague that will solve the world's problem with overpopulation.

We reported last week that Inferno is already off to a good start at the international box office, picking up $50 million in its overseas debut, and its international total has now grown to $132.7 million from a $75 million budget. After Sony hosted the world premiere screening in Florence, Italy last week, Italy became the top international market for Inferno, earning $5 million from 676 screens, while Germany and Russia both pulled in $4.4 million apiece. The film earned $3.8 million in the U.K., followed by $2 million in Spain and $1.2 million in the Netherlands. Inferno also launched in 11 Latin American markets for a combined total of $9 million. Brazil lead the way among the Latin American debuts with $4 million, followed by Mexico ($2.6 million). Southeast Asia generated $6 million in seven markets, led by Taiwan with $1.7 million, India with $1.3 million and Indonesia with $ 1 million. Australia launched with $1.8 million and the UAE took in $1 million.

The top 5 is rounded out by Jack Reacher: Never Go Back with $9.5 million, The Accountant with $8.4 million and Ouija: Origin of Evil with $7 million. The top 10 will be rounded out by The Girl on the Train ($4.2 million), Miss Peregrine's Home for Peculiar Children ($3.9 million), Keeping Up with the Joneses ($3.3 million), Kevin Hart: What Now? ($2.6 million) and Ae Dil Hai Mushkil ($2.1 million). Also debuting in limited release is Magnolia's documentary Gimme Danger, which earned $44,025 from three theaters for a $14,675 per-screen average. No box office data was released for Argentum's romance New Life and Paladin's horror-thriller The Unspoken will debut in limited release.

Last weekend, Moonlight earned $402,075 from four theaters, for an astounding $100,519 per-screen average. That per-screen average was the highest of any movie released this year, and the second best in the past two years, behind only The Revenant, which earned $474,560 from four theaters last year for a per-screen average of $118,640 last December. The critics are already raving about Moonlight, which has an astounding 99% rating on Rotten Tomatoes, with just one "rotten" review out of 79. This weekend, the film expanded to 36 theaters, earning an impressive $900,826 for a $25,023 per-screen average. The film is set for a nationwide expansion set for November 4, going up against Doctor Strange. Depending on how wide the expansion is, and if Moonlight can continue to post impressive numbers this weekend, it may be able to sneak into the top 10.

Looking ahead to next weekend, Marvel's highly-anticipated Doctor Strange will go up against Lionsgate's Hacksaw Ridge and DreamWorks Animation's Trolls in wide release, although no theater counts have been given yet. Also opening in limited theatrical release is Magnolia's documentary Harry Benson: Shoot First, Focus Features' drama Loving and another Magnolia documentary, Peter and the Fire. The Orion Pictures' horror-comedy Trash Fire will also open in limited release on Wednesday, November 2. Take a look at the box office estimates for the top 10 below, for the weekend of October 28.