Brad Pitt is in talks to star in Tree of Life, a drama Terrence Malick wrote and will direct, according to Variety.

Pitt would replace Heath Ledger, who was scheduled to star with Sean Penn in the Malick-directed drama, which begins production in the spring.

Though Penn is booked to play the title character in the Gus Van Sant-directed Harvey Milk, he's still expected to play a supporting role in Tree of Life.