Catherine Keener and Robin Wright Penn are set to star in the Hollywood comedy, What Just Happened? for 2929 Entertainment.

Barry Levinson is directing the film based on an original screenplay by Art Linson; The Hollywood Reporter says it centers on a desperate movie producer (Robert De Niro) trying to survive the treachery of Hollywood and a broken second marriage. Keener will play the head of the studio the producer is courting, while Wright Penn will portray the producer's ex-wife. Stanley Tucci, John Turturro and Kristen Stewart co-star. Bruce Willis and Sean Penn also will be featured in small roles, playing themselves.

What Just Happened? begins shooting this week in Los Angeles.