Luke Wilson's romantic comedy Henry Poole was Here has just locked down its leading lady. According to Variety, Cheryl Hines has decided to jump aboard this wacky train.

The film centers on a man who leaves his normal life behind for a career in debauchery when he learns that he only has six months left to live. He doesn't get too far with his wild ways thanks to his new crazy neighbors.

Mark Pellington is directing the film. It is set to start shooting soon.