Watch Academy Award winner Eddie Redmayne and Alicia Vikander in the official trailer for Focus Features' The Danish Girl. From Academy Award-winning director Tom Hooper, and based on the book by David Ebershoff, the love story opens in New York and Los Angeles on Friday, November 27th, and in additional cities in December. The drama will be opening in limited release against Creed, Victor Frankenstein, The Good Dinosaur and The Night Before.

The remarkable love story inspired by the lives of artists Einar and Gerda Wegener (Academy Award winner Eddie Redmayne and Alicia Vikander), whose marriage and work are cast into the unknown when Einar begins a groundbreaking journey to become one of the world's first transgender women, Lili Elbe. This tender portrait of a marriage asks: What do you do when someone you love wants to change? It starts with a question, a simple favor asked of a husband by his wife on an afternoon chilled by the Baltic wind while both are painting in their studio.

Her portrait model has canceled, and would he mind slipping into a pair of women's shoes and stockings for a few moments so she can finish the painting on time. 'Of course,' he answers. 'Anything at all.' With that, one of the most passionate and unusual love stories of the twentieth century begins. When their portraits become wildly popular in 1920s Copenhagen, Greta encouraged her husband to adopt the female guise. What began as a harmless game led Einer to a metamorphosis and landmark 1931 operation that shocked the world and threatened their love.

Related: Gwenyth Paltrow Joins The Danish Girl

The supporting cast of The Danish Girl includes Amber Heard, Matthias Schoenaerts and Ben Whishaw. Tom Hooper directs from an adapted screenplay by Lucinda Coxon. The director also produces alongside Gail Mutrux (Kinsey), Anne Harrison (Two Family House) and Working Title co-chairs Tim Bevan and Eric Fellner. Linda Reisman is executive-producing The Danish Girl with Ulf Israel of Senator Global Productions.

Eddie Redmayne is coming off his Oscar win for The Theory of Everything, and he recently signed on to play Newt Scamander in the Harry Potter prequel in Fantastic Beasts and Where to Find Them. Alicia Vikander is coming off a critically-acclaimed performance in Ex Machina, and she can currently be seen in The Man from U.N.C.L.E.. Check out the trailer below for The Danish Girl, and let us know what you think of the drama's Oscar chances.