The CW's update of Melrose Place has been given the greenlight with an official pilot order, and set Oscar winner Davis Guggenheim to direct.

According to The Hollywood Reporter, in other news filmmaker Jeffrey Nachmanoff has signed on to direct the Fox drama pilot Masterwork.

In pilot castings, Zosia Mamet, daughter of playwright-filmmaker David Mamet, has landed her first starring role on Fox's comedy pilot Absolutely Fabulous. Toni Trucks also has been cast in Ab Fab.

Elsewhere, Jason George and Sarah Drew have joined ABC's drama pilot Inside the Box, and Diego Klattenhoff has been added to NBC's drama pilot Mercy.

The CBS Par-produced Melrose Place, a remake of the '90s series about a group of twentysomethings living in the trendy Melrose neighborhood of Los Angeles, was written by Darren Swimmer and Todd Slavkin (Smallville), who will serve as exec producers/showrunners. Endeavor-repped Guggenheim, who won an Oscar for An Inconvenient Truth, will exec produce as well.

Guggenheim, who is under a deal at CBS Par, is known for directing edgier dramas such as Deadwood and 24, but early in his career, he helmed lighter fare including Fox's Party of Five.

For his TV debut, Nachmanoff, who most recently wrote and directed Traitor, will tackle the international The Da Vinci Code-type adventure Masterwork, from 20th TV.

Inside the Box, from ABC Studios, revolves around an ambitious female news producer and her colleagues at a Washington network news bureau. George will play an on-camera correspondent. Drew will play a new peon at the network.

Based on the British series, the Sony-produced Ab Fab revolves around neurotic fashion publicist Eddie (Kathryn Hahn) and her best friend Patsy (Kristen Johnson), an outrageous fashion editor, who drive Eddie's sensible teen daughter, Saffron (Mamet), up the wall with their wild behavior.

The UMS-produced Mercy revolves around three nurses who bond through the ups and downs of their professional and personal lives.

Klattenhoff will play a contractor and blue-collar worker who is married to one of the nurses.