Now that Ryan Reynolds has been officially confirmed to return as Deadpool, with production set to begin in March, 20th Century Fox is filling out the supporting roles, with actors T.J. Miller and Ed Skrein both in talks to join the cast. The Wrap reports that T.J. Miller will provide, "an additional comic voice to compliment Deadpool," although his exact character was not specified. Ed Skrein is said to be further along in negotiations than T.J. Miller, with the site speculating that he could be eyed for the villain.

Ryan Reynolds originally played Deadpool in the 2009 superhero prequel X-Men Origins: Wolverine, with talk of a spin-off featuring the "Merc With a Mouth" surfacing shortly thereafter. Following years of development, test footage shot by director Tim Miller leaked back in July, which was received with enormous support from the fans, leading to 20th Century Fox announcing a 2016 release back in September. No story details have been revealed at this time, but the project was confirmed to be part of the X-Men cinematic universe back in October.

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Rhett Reese and Paul Wernick wrote the screenplay adaptation, based on the Marvel comic book created by Rob Liefeld and Fabian Nicieza. In the comics, Deadpool often "breaks the fourth wall" and talks directly to the audience, although it isn't known if this aspect will be utilized. There was talk in September that the adaptation will be PG-13, instead of R, although it was revealed a few days later that the exact rating has not been determined.

T.J. Miller most recently starred in Transformers: Age of Extinction, and he also voiced roles in How to Train Your Dragon 2 and Big Hero 6. He will next be seen in Search Party and in the second season of HBO's Silicon Valley. Ed Skrein will next be seen in The Transporter Legacy, arriving in theaters June 19, 2015.