Debra Messing has signed on to star in the new series, The Starter Wife for the USA Network.

The show is based on Gigi Levangie Grazer's best-selling novel about the quest of a divorced woman (Messing) to redefine herself after years of marriage to a Hollywood studio head, says The Hollywood Reporter.

Production for The Starter Wife is set to begin late this year in Australia; look for it to air in 2007 on USA.