Love and Other Drugs is the latest drama from Edward Zwick, the director behind The Last Samurai and Defiance. Anne Hathaway stars as Maggie, an alluring free spirit who won't let anyone, or anything, tie her down. But she meets her match in Jamie (Jake Gyllenhaal), whose relentless and nearly infallible charm serve him well with the ladies and in the cutthroat world of pharmaceutical sales. Maggie and Jamie's evolving relationship takes them both by surprise, as they find themselves under the influence of the ultimate drug: Love. AFI has provided us with an exclusive interview featuring Jake Gyllenhaal, Hank Azaria, and director Edward Zwick, which you can check out in the clip below:

B. Alan Orange