Lionsgate has released the first trailer for the 3D animated Alpha and Omega about two mismatched wolves who have to travel together for a thousand miles to get back to their pack. Get your first look below.

Opening in theaters September 17, Alpha and Omega centers on Kate and Humphrey, two wolves who are trying to get home after being taken by park rangers and shipped halfway across the country. Humphrey is an Omega wolf, whose days are about quick wit, snappy one-liners and hanging with his motley crew of fun-loving wolves and video-gaming squirrels. Kate is an Alpha: duty, discipline and sleek Lara Croft eye-popping moves fuel her fire. Humphrey's motto - make 'em laugh. Kate's motto - I'm the boss. And they have a thousand miles to go.