Series stars Danielle Panabaker (Caitlin Snow) and Carlos Valdes (Cisco Ramon) discuss the particle accelerator explosion at S.T.A.R. Labs that gives Barry Allen (Grant Gustin) his super speed, but destroys all the work they have been doing. For those who follow the DC Comics, Ramon eventually becomes the superhero Vibe, while Snow ends up becoming the villainous Killer Frost. While he isn't shown or mentioned by name, Snow also mentions that the explosion killed her fiancee, Ronnie Raymond (Robbie Amell), who turns into one half of Firestorm. While it hasn't been confirmed if Vibe or Killer Frost will be popping up on the show yet, it's clear the particle accelerator accident is a catalyst for several different storylines in The Flash.
After a particle accelerator causes a freak storm, CSI Investigator Barry Allen is struck by lightning and falls into a coma. Months later he awakens with the power of super speed, granting him the ability to move through Central City like an unseen guardian angel. Though initially excited by his newfound powers, Barry is shocked to discover he is not the only "meta-human" who was created in the wake of the accelerator explosion - and not everyone is using their new powers for good. Barry partners with S.T.A.R. Labs and dedicates his life to protect the innocent. For now, only a few close friends and associates know that Barry is literally the fastest man alive, but it won't be long before the world learns what Barry Allen has become...The Flash.