This is the second major departure this season. As you might recall, Jorja Fox made her final appearance as Sara in November.
The article states:
Meanwhile, CSI execs aren't wasting any time searching for Dourdan's replacement. I'm told producers have put out a casting call for a new male series regular in his late twenties to early thirties to play Ray Santoro, a "handsome, smart and athletic" CSI who transfers from Henderson to join the graveyard shift at the Las Vegas crime lab.
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