Gemma Arterton (St. Trinian's) has been cast as one of the female leads in Bond 22, according to Empire Online.

The site reports that:

What's not absolutely certain yet is whether Arterton will be the main Bond girl, like Eva Green in Casino Royale, or one of the peripheral lovelies like Caterina Murino and that other one. But what we're hearing suggests that she'll be in a fairly major role.

The 22nd James Bond adventure will be released by Columbia Pictures on November 7, 2008 with Daniel Craig reprising the role of the legendary British secret agent.