Sony Pictures' Inferno won't debut in domestic theaters until October 28, but this adaptation of Dan Brown's Robert Langdon novel debuted in a number of international markets this weekend. Director Ron Howard's thriller earned an impressive $50 million in 53 international markets. This highly-anticipated adaptation, which is the third Robert Langdon adaptation starring Tom Hanks, following The Da Vinci Code and Angels & Demons, was produced under a $75 million budget.

Variety reports that the film held its world premiere in Florence, Italy last weekend, and Italy was the top international market for this thriller, which isn't surprising since the film is set in the country. The movie earned $5 million in Italy from 676 screens, while Germany and Russia both pulled in $4.4 million apiece. The film earned $3.8 million in the U.K., followed by $2 million in Spain and $1.2 million in the Netherlands. Inferno also launched in 11 Latin American markets for a combined total of $9 million. Brazil lead the way among the Latin American debuts with $4 million, followed by Mexico ($2.6 million). Southeast Asia generated $6 million in seven markets, led by Taiwan with $1.7 milliom, India with $1.3 million and Indonesia with $ 1 million. Australia launched with $1.8 million and the UAE took in $1 million.

This new adventure finds the famous symbologist (Tom Hanks) on a trail of clues tied to the great Dante himself. When Langdon wakes up in an Italian hospital with amnesia, he teams up with Sienna Brooks (Felicity Jones), a doctor he hopes will help him recover his memories. Together, they race across Europe and against the clock to stop a madman from unleashing a global virus that would wipe out half of the world's population.

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Academy Award winner Ron Howard returns to direct the latest bestseller in Dan Brown's billion-dollar Robert Langdon series, Inferno. The film's screenplay is written by David Koepp, based upon the novel by Dan Brown, with Brian Grazer and Ron Howard serving as the producers. Sony has set an October 28 release date for Inferno, which is currently the only movie slated to open in wide release that weekend, but it will debut one week before Marvel's highly-anticipated Doctor Strange.

Tom Hanks and Ron Howard's The Da Vinci Code and Angels & Demons have both earned over $1.2 billion worldwide to date. The supporting cast for Inferno is rounded out by Irrfan Khan as Harry Sims, a.k.a. The Provost, Omar Sy as Christoph Bruder and Sidse Babett Knudsen as Dr. Elizabeth Sinskey, the head of the World Health Organization. Ben Foster is playing the villain Bertrand Zobrist, a scientist trying to unleash a global plague that will solve the world's problem with overpopulation. It remains to be seen whether Inferno will become a big hit at the domestic box office in just a few weeks.