Once upon a time, Tom Hanks and Meg Ryan were known as America's sweethearts. The duo first paired up on the big screen for 1990's Joe Versus the Volcano. They would also go onto appear together in 1993's Sleepless in Seattle followed by 1998's You've Got Mail. They haven't been seen together since that time. But that all changes with the upcoming WWII drama Ithaca, which brings a stirring reunion between the two lost and wandering soles.

Ithaca marks Meg Ryan's directorial debut after the actress took some time away from appearing in blockbuster romantic comedies. The movie is a coming-of-age tale for one teenage boy, and doesn't revolve around another loving relationship between the two former co-stars. In fact, the pair weren't seen together in the trailer that dropped last month. And they only share a fleeting few moments together on screen. Entertainment Weekly has a first look at this reunion.

Tom Hanks only has a brief cameo in Ithaca. He plays the late husband of Meg Ryan's character. Meg Ryan and Tom Hanks obviously enjoy each other's company. And speaking with EW, Ryan had nothing but praise for her once and future co-star. She says this.

"He's just so dear. He so did not have to do that. It took him a day to [shoot his scene]. At the end of his time, he says to the crew, 'All right, gather 'round. Listen, I know we've gotten to know each other very well over the last 10 hours together, but I just want to thank you for being here for my friend Meg.' It was such an act of friendship. I love him so much."

Meg Ryan adapted Ithaca from the William Saroyan novel The Human Comedy, working alongside screenwriter Erik Jendresen. The movie had its premiere last year at the Middleburg Film Festival. And it has gone onto screen at several other film festivals since then including ones in Savannah, Dubai, and Sonoma. It also played at Geena Davis' female-focused Bentonville Film Festival this past May.

Alex Neustaedter stars in Ithaca as Homer Macauley, a teenager whose first job is as a bicycle telegraph messenger during WWII. The boy's family is awaiting the return of Homer's older brother Marcus, played by Meg Ryan's son Jack Quaid. Marcus was recruited to fight in the war. Sam Shepard and Hamish Linklater also star in the movie alongside Meg Ryan, who takes on a supporting role. The movie opens in theaters throughout the country in limited release on September 9. But you don't have to wait that long to see Tom Hanks and Meg Ryan reunite on the big screen, which we've included here alongside the first trailer and poster.