Brokeback Mountain couple Jake Gyllenhaal and Anne Hathaway will give their love another try in Love and Other Drugs, directed by Ed Zwick for Fox 2000/New Regency.

According to The Hollywood Reporter, the project was formerly titled Pharma, and is adapted by Charles Randolph (The Interpreter) from Jamie Reidy's nonfiction book "Hard Sell: The Evolution of a Viagra Salesman."

Reidy was a drug rep for Pfizer in the late 1990s who eventually wrote a memoir that shined a light on the practices of the pharmaceutical industry. Gyllenhaal will play the salesman, who begins a relationship with a woman who has Parkinson's (Hathaway) while on one of his sales calls. Their love story plays out in the political and social context of the time.

Fox is in the process of obtaining the rights from Universal, which had put the project into turnaround.

The filmmakers hope to begin shooting in the fall.