The troubled Western Jane Got a Gun suffered yet another setback today, when Bradley Cooper was forced to step away from the project. The actor is currently shooting American Hustle in Boston for director David O. Russell, and the schedule was pushed back due to the Boston Marathon terrorist bombings. He also has press obligations for The Hangover Part III, which lead to his departure.

The producers are currently trying to find a replacement as quickly as possible, seeking actors such as Jake Gyllenhaal, Tobey Maguire, and Tom Hiddleston to fill their latest casting void. Bradley Cooper himself was a replacement for Jude Law, who backed out after director Lynne Ramsay abruptly quit on the first day of shooting. Gavin O'Connor is now directing, from a screenplay by Brian Duffield.

Natalie Portman stars as the title character, whose husband (Noah Emmerich) comes home riddled with bullet wounds. When the band of outlaws comes to Jane's farm to finish the job, she seeks help from a former lover (Joel Edgerton) to ward off these gunmen.

Related: Lynne Ramsay Replaced by Warrior Director Gavin O'Connor on Jane Got a Gun

Production is currently under way in New Mexico. The main villain's scenes will not be shot until June.