Legendary actress Jane Seymour will guest-star in three episodes of the new ABC comedy series, In Case of Emergency. Her first episode airs WEDNESDAY, FEBRUARY 14 (9:30-10:00 p.m., ET/PT).

Seymour will play Jason's (David Arquette) mother, Donna. In her first episode, "Oh, Henry!," Jason, on the verge of going to jail, can cut a deal if he rats on his Uncle Henry, who happens to be Donna's favorite brother. Jason begs Harry (Jonathan Silverman) to help him with Donna because she always favored Harry over him. Things quickly get hot when Donna starts flirting with Harry and makes a pass at him. But the fireworks don't end there, as Donna asks Harry to give her a ride home - alone.

Winner of multiple Emmy and Golden Globe Awards and recipient of the Officer of the British Empire (OBE) in the year 2000, bestowed upon her by Queen Elizabeth II at Buckingham Palace, Seymour has proven her talents in virtually all media, the Broadway stage, motion pictures and television. She recently starred in the box office hit Wedding Crashers, with Owen Wilson and Vince Vaughn, in which she played the sexually charged wife of Christopher Walken. Next up for her is the comedy feature Blind Dating, in which Seymour stars with Chris Pine as a psychiatrist who has a hard time remaining clothed while counseling her patient.

In Case of Emergency stars Arquette (Scream), Silverman (Weekend at Bernie's, Caddyshack 2), Greg Germann (All McBeal) as Sherman Yablonsky and Kelly Hu (The Scorpion King) as Kelly Lee. Also starring are Lori Loughlin (Full House, Summerland) as Dr. Joanna and Jackson Bond (The Invasion) as Dylan.