Paramount Vantage has released the first trailer for Jeff Who Lives at Home, the latest indie comedy from Jay Duplass and Mark Duplass, which opens in theaters March 16. Click on the video player below for your first look at this comedy starring Jason Segel, Ed Helms, Judy Greer, Mark Duplass, and Susan Sarandon. You can also check out the first poster for Jeff Who Lives at Home below the trailer.

On his way to the store to buy wood glue, Jeff looks for signs from the universe to determine his path. However, a series of comedic and unexpected events leads him to cross paths with his family in the strangest of locations and circumstances. Jeff just may find the meaning of his life... and if he's lucky, pick up the wood glue as well.