Kelsey Grammer has been tapped to direct the CBS comedy pilot My Ex-Life. The story revolves around two divorced couples and the way they deal with their lives after divorce. The show, from 20th Century Fox TV, stars Tom Cavanagh and Gillian Vigman.

Meanwhile, the CW has picked up the comedy pilot Flirt, starring Wayne Brady. In other casting news, The Hollywood Reporter says Bo Derek has joined My Network TV's drama series Secret Obsessions, Constance Zimmer has come on board ABC's comedy pilot 52 Fights, and Danielle Panabaker has been added to the cast of CBS' drama pilot Shark.