Here's what Mark Millar said on the show, as transcribed by website Bleeding Cool:
"The estimate is [Kick-Ass] will do 100 to 150 million on DVD based on the American sales, you know, so it'll end up making a quarter of a billion on a 28 million investment. So It should be okay. So the sequel's greenlit, we can go ahead and do the follow up now, you know? The first made so much compared to what it cost it would be crazy not to."
Director Matthew Vaughn is expected to make Kick-Ass 2: Balls to the Wall his next project after he finishes work on X-Men: First Class, which hits theaters June 3rd of 2011. Aaron Johnson, Chloe Moretz, and Christopher Mintz-Plasse have all expressed interest in returning for the sequel.
We'll be sure to keep you posted with any further details on Kick-Ass 2: Balls to the Wall as they're made available.