According to The Hollywood Reporter, Nicole Kidman is in final negotiations to topline Invasion, a sci-fi thriller being directed by Oliver Hirschbiegel for Warner Bros. Pictures. Joel Silver is producing.

The story takes place after a mysterious epidemic alters the behavior of human beings and follows a Washington psychiatrist (Kidman) who discovers that its origins are extraterrestrial. She must fight to protect her son, who may hold the key to stopping the invasion. The project is neither a reimagining nor a remake of Invasion of the Body Snatchers. The project originated as a remake, but when writer David Kajganich turned in his take, the studio thought it had something fresh on its hands.

"It's a very insidious story about how the end of the world can come through science and disease and not through explosions," Silver said. "Oliver really understands the kind of dark character study that this is going to be. He fell in love with Nicole, he said he really wanted her, and it took us a while to make the deal."

A late September shoot in Baltimore is being eyed for the pic, which is being co-financed by Village Roadshow Pictures.

For Kidman, Invasion would be a return to a genre she hasn't done since the ghost story The Others in 2001.

Hirschbiegel directed the Academy Award-nominated German-language film Downfall, which has grossed more than $87 million worldwide. His other credits include Das Experiment, Germany's entry for the Academy Awards in 2002.