The story centers on Liv Tyler's character, Catherine Rigby, who spends several months alone in space, to test a pharmaceutical company's new drugs. When the woman somehow becomes pregnant, paranoia sets in as Catherine begins to think she may be stranded in space. Here's what Ti West had to say about bringing Liv Tyler on board.
"Although it is still somewhat of a horror film, it is much more psychological than any of my previous efforts. It was essential that I find an actress who could portray a wide range of emotion and always earn the audience's sympathy no matter what the situation. As soon as I sat down with Liv, it was obvious she was the one."
Ted Hope and Peter Phok are producing through Double Hope Films. No production schedule was given for The Side Effect.