MadTV celebrates 300 episodes of unrivaled pop-culture parodies and politically incorrect humor Saturday, Nov. 17 (11:00-Midnight ET/PT) on FOX. Former cast members Mo Collins and Debra Wilson Skelton return to toast 13 seasons of late-night laughs from the historic Henry Fonda Theater in Hollywood.

In the episode Wilson reprises her heralded "Whitney Houston" impression as she belts out a special tune commemorating MadTV's most outrageously magic moments, and Collins appears as the beloved Midwest fuss-pot, "Lorraine." The celebration continues with montages highlighting 12 seasons of music-video spoofs, TV show take-offs, movie parodies, fake commercials and classic send-ups featuring MADtv's favorite characters and cast members.

MadTV's edgy humor has made this award-winning sketch comedy show a FOX Saturday-night staple. Noted for its signature characters, celebrity impersonations and biting pop-culture commentaries, MadTV features cast members Michael McDonald, Bobby Lee, Nicole Parker, Keegan-Michael Key, Jordan Peele, Arden Myrin, Crista Flanagan, Anjelah Johnson, Johnny Sanchez, Daheli Hall and Dan Oster.

Related: Jerry O'Connell to Guest Star in Mad TV

Dont't forget to also check out: MadTV