According to the actor the show ends in "an incredibly powerful, very sad and beautiful way. I think is going to be pretty awesome."
He went on to say, "I think it is going to be very satisfying and cathartic and redemptive and beautiful. I've talked to Damon pretty extensively and every time I talk to him it's sort of surprising how moving it is just to talk about it."
As for how season six begins?
It will start with Juliet and what happened when she set off that hydrogen bomb. "It's very surprising and probably fairly confusing initially to the audience." Fox says.
"Like a third of the way in [to the season] I would guess we are going to [settle] in one time frame and it will be very linear-no more flashbacks, nothing. It will be on the island and sort of a final conflict to the end," Fox offered
The actor ended the interview by saying that the storylines from earlier seasons will be resolved and that the tension between Jack and Locke (Terry O'Quinn) "will come head to head" during this season.