Meryl Streep and Philip Seymour Hoffman will star in the adaptation of the Broadway hit, Doubt for Miramax Films.

From writer-director John Patrick Shanley, Streep will play Sister Aloysius, a nun and principal of a New York Catholic school who accuses a priest (Hoffman) of sexually abusing one of his students, leading to an escalating debate over his guilt or innocence. According to The Hollywood Reporter, the role of Sister James, another leading role, has yet to be cast.

No word on a production schedule for Doubt.