Garry Marshall directs a huge ensemble cast including Halle Berry, Robert De Niro, and Ashton Kutcher in this holiday romance.
The Sitter takes second place with $10 million while The Twilight Saga: Breaking Dawn earns $7.9 million in third place.
Or will Jonah Hill's The Sitter overtake this ensemble romantic comedy for box office supremacy?
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Viewers can watch all of the celebrity arrivals at the Hollywood premiere starting at 6 PM PST tonight.
Garry Marshall directs an ensemble cast including Robert De Niro, Ashton Kutcher, and Halle Berry in this Warner Bros. holiday comedy.
The entire ensemble cast can be found on this new one-sheet for Garry Marshall's holiday-themed romance.
Garry Marshall directs this ensemble romantic comedy about several New Yorkers who connect with each other over the holiday.
Garry Marshall directs an all-star ensemble cast including Robert De Niro, Halle Berry, Jessica Biel, and many more in this romantic comedy.
The rapper-actor will play a NYPD cop who interacts with the director of the Times Square event, portrayed by Hilary Swank.
Carla Gugino will play a doctor, while Halle Berry re-joins the ensemble after dropping out due to a custody battle.
The actress will play a lonely nurse who has no one to spend the holiday with in Garry Marshall's romantic comedy.
Katherine Heigl will play the ex-lover of Jon Bon Jovi's character in Garry Marshall's romantic ensemble.
Seacrest will play himself in a cameo while Ice Cube portrays an NYPD cop and Duhamel plays a romantic in search of a New Year's date.
Inglourious Basterds star Til Schweiger also joins Garry Marshall's latest star-studded holiday-themed project.
Halle Berry and Zac Efron are also in negotiations for Garry Marshall's latest romantic holiday-comedy.