Sanctum dives into second place with only $9.2 million, while No Strings Attached falls to third.
Or can The Roommate scare audiences enough to reach number one?
Leighton Meester and Cam Gigandet star in this college thriller about a creepy dorm roommate.
The studio also announced release date changes for Underworld 4, Takers and The Roommate.
Matt Lanter has also signed on to the cast of the new thriller.