Walt Disney Pictures has released a new trailer for Muppets Most Wanted, which includes the opening musical number set directly after 2011's The Muppets, when these lovable characters first learn that they are doing a sequel. This sequence also features stars Tina Fey, Ty Burrell, Ricky Gervais, Jean Dujardin, Christoph Waltz, Sean Combs, Danny Trejo and, of course, Kermit the Frog, Miss Piggy and the rest of the Muppets gang. Take a look at the latest footage from director James Bobin's sequel, arriving in theaters March 21.

Disney's Muppets Most Wanted takes the entire Muppets gang on a global tour, selling out grand theaters in some of Europe's most exciting destinations, including Berlin, Madrid, Dublin and London. But mayhem follows the Muppets overseas, as they find themselves unwittingly entangled in an international crime caper headed by Constantine-the World's Number One Criminal and a dead ringer for Kermit-and his dastardly sidekick Dominic, a.k.a. Number Two, portrayed by Ricky Gervais. The film stars Tina Fey as Nadya, a feisty prison guard, and Ty Burrell as Interpol agent Jean Pierre Napoleon.

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